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Targeted Oral Therapeutics

Advancing Precision Medicines for Immune-Mediated Diseases

Developing differentiated oral therapies designed to transform the treatment of immune-mediated and fibrotic diseases, beginning with inflammatory bowel disease.

Clinical-Stage Company

Advancing lead program through Phase 2 clinical development.

Differentiated Oral Medicines

Designed to improve efficacy, safety and patient convenience with early clinical data showing encouraging response rates.

Immune & Fibrotic Diseases

Focused on areas of significant unmet medical need.

About Palisade Bio

Palisade Bio is a clinical-stage biopharmaceutical company developing differentiated oral therapeutics for immune-mediated and fibrotic diseases. Our lead program, PALI-2108, is advancing through Phase 2 clinical development for inflammatory bowel disease.

Our Approach

We seek to develop differentiated oral medicines by combining compelling biology, thoughtful drug design and disciplined clinical development.

  • Differentiated Science
    Pursuing therapeutic approaches with the potential to meaningfully improve patient care.
  • Patient-Focused Development
    Prioritizing efficacy, safety and convenience in the development of oral medicines.
  • Disciplined Execution
    Advancing programs through focused, data-driven development.
Program
Preclinical Phase 1 Phase 2 Phase 3
PALI-2108

Ulcerative Colitis (UC)

Phase 2 Ongoing

PALI-2108

Crohn's Disease (CD)

Phase 2 Planned

PALI-2108

Fibrostenotic Crohn's disease

Phase 1b Completed