Overview

Development Programs

Differentiated prodrug candidates initially targeting established IBD market with potential to address shortcomings of existing therapies

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PALI-2108 (PDE4 prodrug, once daily)

Indication
Ulcerative Colitis (UC)

Status
Phase 2

Highlights
Completed and reported topline data for Ph1

IND and Ph2 expected to commence in 2026

Indication
Crohn’s Disease (CD)

Status
Phase 2

Highlights
Completed and reported topline data for Ph1

IND and Ph2 expected to commence in 2026/27
(finalizing study design)

PDE4 Platform

Precision Medicine Approach

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