Overview
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Quarterlies
Date | Form | Description | Download |
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Nov 12, 2024 | 10-Q | Quarterly Report - 2024 Q3 | ![]() ![]() ![]() ![]() ![]() |
Aug 12, 2024 | 10-Q | Quarterly Report - 2024 Q2 | ![]() ![]() ![]() ![]() ![]() |
May 13, 2024 | 10-Q | Quarterly Report - 2024 Q1 | ![]() ![]() ![]() ![]() ![]() |
Events
Session Title: Transcriptional, Epigenetic and Genetic Regulation of GI Function and Disease
Session Date & Time: May 4, 12:30 PM to 1:30 PM PDT
Title: A BIOINFORMATIC APPROACH TO PALI-2108 TREATMENT IN ULCERATIVE COLITIS REVEALS THE POTENTIAL FOR ANTI-FIBROTIC EFFICACY WITH LOCAL PDE4 INHIBITION IN INTESTINAL FIBROSIS
DDW Poster of Distinction – Poster Presentation
Session Title: In Vivo Models of Gastrointestinal Disorders
Session Date & Time: May 5, 12:30 PM to 1:30 PM PDT
Title: PALI-2108, A COLON-SPECIFIC PDE4 INHIBITOR PRODRUG, IS BIOACTIVATED IN THE COLON AND REDUCES COLON TISSUE PDE4B IN A DOSE-DEPENDENT MANNER, INCREASING C-AMP AND SUPPRESSING TNF- IN A MOUSE MODEL OF COLI
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Company
Palisade Bio is a clinical stage biopharmaceutical company dedicated to advancing next-generation precision therapies for immune, inflammatory, and fibrotic diseases. These conditions represent a significant unmet need, leading to chronic organ dysfunction, damage and even failure due to abnormal immune responses and persistent inflammation.
Our lead program, PALI-2108, is a microbiota-activated PDE4 inhibitor prodrug in development for the treatment of moderate-to-severe ulcerative colitis. Ulcerative colitis represents a significant challenge for patients, who are in need of therapies that provide effective remission rates, are non-immunosuppressive and have improved safety.